Description

2-Chloro-6-Phenylisonicotinoylchloride is a high-purity, reactive chemical intermediate of significant importance in advanced organic synthesis. This compound matters for its role as a key building block in the creation of complex heterocyclic molecules, particularly in the pharmaceutical sector. It is primarily needed by research and development chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of active ingredients and novel compounds.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, leveraging its chlorinated pyridine core structure.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in catalytic processes and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of advanced organic electronic materials and functional polymers.
• Custom Synthesis and Contract Manufacturing: A valuable reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences market.

Basic Information

Product Name	2-Chloro-6-Phenylisonicotinoylchloride
CAS No.	1045325-76-5
Molecular Formula	C12H7Cl2NO
Molecular Weight	252.10 g/mol
Synonyms	2-Chloro-6-phenylpyridine-4-carbonyl chloride; 2-Chloro-6-phenylisonicotinic acid chloride; 4-Pyridinecarbonyl chloride, 2-chloro-6-phenyl-; 2-Chloro-6-phenyl-4-pyridinecarbonyl chloride; 6-Phenyl-2-chloroisonicotinoyl chloride; Isonicotinoyl chloride, 2-chloro-6-phenyl-
EINECS	Contact for details

Quality Control

Our 2-Chloro-6-Phenylisonicotinoylchloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Assay	97.0 - 103.0 %
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.