Description

Methyl 5-Chloro-1H-Imidazo[4,5-B]Pyridine-2-Carboxylate is a high-purity heterocyclic building block of significant importance in advanced organic synthesis. This compound serves as a critical intermediate for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, enabling the construction of complex molecular architectures. It is primarily sought after by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and fine chemical sectors for lead optimization and process development.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of potential drug candidates, particularly in oncology, antiviral, and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its fused imidazopyridine core.
• Chemical Biology Probe: Serves as a scaffold for creating molecular probes to study enzyme function and biological pathways.
• Material Science Precursor: Potential building block for advanced organic electronic materials and ligands for catalysis.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations for custom synthesis and scale-up projects.
• Academic Research: Utilized in university and institutional labs for methodological studies and novel heterocycle chemistry.

Basic Information

Product Name	Methyl 5-Chloro-1H-Imidazo[4,5-B]Pyridine-2-Carboxylate
CAS No.	1044772-73-7
Molecular Formula	C8H6ClN3O2
Molecular Weight	211.60 g/mol
Synonyms	5-Chloro-1H-imidazo[4,5-b]pyridine-2-carboxylic acid methyl ester; Methyl 5-chloro-1H-imidazo[4,5-b]pyridine-2-carboxylate; 1H-Imidazo[4,5-b]pyridine-2-carboxylic acid, 5-chloro-, methyl ester; 5-Chloro-1H-imidazo[4,5-b]pyridine-2-carboxylic acid methyl ester; Methyl 5-chloroimidazo[4,5-b]pyridine-2-carboxylate; CAS 1044772-73-7
EINECS	Contact for details

Quality Control

Our Methyl 5-Chloro-1H-Imidazo[4,5-B]Pyridine-2-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.