Description

3-Bromo-5-Cyclopropylpyridine is a high-value brominated pyridine derivative, serving as a versatile and critical building block in advanced organic synthesis. Its unique structure, featuring both a bromine substituent and a cyclopropyl ring, makes it an essential intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the cyclopropylpyridine moiety can contribute to specific biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in transition metal catalysis and organometallic chemistry.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport layers or light-emitting components, due to its electron-deficient aromatic system.
• Chemical Biology Probes: Utilized to create tagged molecules or inhibitors for studying biological pathways and protein functions.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.

Basic Information

Product Name	3-Bromo-5-Cyclopropylpyridine
CAS No.	1044210-57-2
Molecular Formula	C8H8BrN
Molecular Weight	198.06 g/mol
Synonyms	5-Bromo-3-cyclopropylpyridine; 3-Cyclopropyl-5-bromopyridine; 3-Bromo-5-cyclopropylpyridine; Pyridine, 3-bromo-5-cyclopropyl-; 1044210-57-2
EINECS	Contact for details

Quality Control

Our 3-Bromo-5-Cyclopropylpyridine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to confirm identity and purity. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment. We support cGMP (current Good Manufacturing Practice) standards for applications requiring the highest level of quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.