Description

tert-Butyl 4-((tert-Butoxycarbonyl)Amino)-2,6-Dichloronicotinate is a high-purity, protected nicotinic acid derivative serving as a critical building block in advanced organic synthesis. This compound is essential for researchers and manufacturers requiring precise molecular architecture, particularly in the development of complex heterocyclic compounds. It is primarily utilized by the pharmaceutical and agrochemical industries for the research and synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly those targeting specific enzyme inhibitors or receptor modulators.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, leveraging its dichloronicotinate core for bioactive molecule construction.
• Chemical Research & Development: Serves as a versatile precursor in academic and industrial labs for exploring new chemical entities and reaction pathways.
• Peptide Mimetics & Conjugate Chemistry: The Boc-protected amino group makes it suitable for constructing peptide-like structures or conjugating with other molecular fragments.
• Ligand Synthesis for Catalysis: Potential use in the development of specialized ligands for metal-catalyzed reactions due to its nitrogen-containing heterocycle.
• Material Science Precursor: Can be employed in the synthesis of functionalized organic materials or metal-organic frameworks (MOFs).

Basic Information

Product Name	tert-Butyl 4-((tert-Butoxycarbonyl)Amino)-2,6-Dichloronicotinate
CAS No.	1044148-88-0
Molecular Formula	C15H20Cl2N2O4
Molecular Weight	363.24 g/mol
Synonyms	tert-Butyl 4-[(tert-butoxycarbonyl)amino]-2,6-dichloropyridine-3-carboxylate; 2,6-Dichloro-4-[(tert-butoxycarbonyl)amino]nicotinic acid tert-butyl ester; 4-(Boc-amino)-2,6-dichloronicotinic acid tert-butyl ester; Boc-4-Amino-2,6-dichloronicotinic acid tert-butyl ester; tert-Butyl 4-(N-Boc-amino)-2,6-dichloronicotinate; 1044148-88-0; 2,6-Dichloro-4-((tert-butoxycarbonyl)amino)nicotinic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-((tert-Butoxycarbonyl)Amino)-2,6-Dichloronicotinate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.