Description

2-Oxaspiro[4.5]Decan-1-One, 8-[[(4-Methylphenyl)Sulfonyl]Oxy]- is a high-purity, advanced pharmaceutical intermediate characterized by its complex spirocyclic structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs) and fine chemicals, offering a key building block for medicinal chemistry research and development. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new therapeutic agents and high-value compounds.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the multi-step synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing spirocyclic and bridged ring systems in drug discovery programs to explore new chemical space and improve drug-like properties.
• Process Chemistry Development: Employed in route scouting and optimization for the scalable production of target molecules under Good Manufacturing Practice (GMP) conditions.
• Agrochemical Synthesis: Acts as a key intermediate in the development of novel pesticides and herbicides with unique modes of action.
• Fine Chemical Production: Utilized in the manufacture of specialty chemicals, flavors, fragrances, and advanced materials requiring specific stereochemistry.
• Academic & Institutional Research: Supplied to universities and research institutes for fundamental studies in organic synthesis and methodology development.

Basic Information

Item	Details
Product Name	2-Oxaspiro[4.5]Decan-1-One, 8-[[(4-Methylphenyl)Sulfonyl]Oxy]-
CAS No.	1043908-54-8
Molecular Formula	C16H20O5S
Molecular Weight	324.39 g/mol
Synonyms	8-[(4-Methylphenyl)sulfonyl]oxy]-2-oxaspiro[4.5]decan-1-one; 8-(p-Toluenesulfonyloxy)-2-oxaspiro[4.5]decan-1-one; 2-Oxaspiro[4.5]decan-1-one, 8-[(4-methylphenyl)sulfonyl]oxy]-; 8-(Tosyloxy)-2-oxaspiro[4.5]decan-1-one; CAS 1043908-54-8
EINECS	Contact for details

Quality Control

Every batch of 2-Oxaspiro[4.5]Decan-1-One, 8-[[(4-Methylphenyl)Sulfonyl]Oxy]- is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure high purity and batch-to-batch consistency suitable for research and development applications. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.