Description

[1,2,4]Triazolo[1,5-A]Pyridine-6-Ethanamine, β-[[(1,1-Dimethylethyl)Dimethylsilyl]Oxy]-α-Methyl- is a sophisticated, high-purity organic intermediate featuring a fused triazolopyridine core protected by a tert-butyldimethylsilyl (TBDMS) ether group. This compound matters as a critical building block in advanced pharmaceutical research and development, enabling the synthesis of complex molecules with potential therapeutic activity. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the triazolopyridine moiety can contribute to biological activity.
• Ligand and Catalyst Development: Serves as a precursor for nitrogen-containing ligands used in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport layers or light-emitting components, due to its conjugated heterocyclic system.
• Chemical Biology Probes: Utilized to develop molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis and Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Item	Detail
Product Name	[1,2,4]Triazolo[1,5-A]Pyridine-6-Ethanamine, β-[[(1,1-Dimethylethyl)Dimethylsilyl]Oxy]-α-Methyl-
CAS No.	1043907-96-5
Molecular Formula	C15H26N4OSi
Molecular Weight	306.48 g/mol
Synonyms	6-[(tert-Butyldimethylsilyloxy)methyl]-1,2,4-triazolo[1,5-a]pyridin-2-amine; 2-Amino-6-[[(1,1-dimethylethyl)dimethylsilyl]oxymethyl][1,2,4]triazolo[1,5-a]pyridine; TBDMS-protected 1,2,4-triazolo[1,5-a]pyridine-6-ethanamine derivative; β-[(tert-Butyldimethylsilyl)oxy]-α-methyl-[1,2,4]triazolo[1,5-a]pyridine-6-ethanamine; 1043907-96-5; 1,2,4-Triazolo[1,5-a]pyridine-6-ethanamine, β-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-α-methyl-
EINECS	Contact for details

Quality Control

Our [1,2,4]Triazolo[1,5-A]Pyridine-6-Ethanamine, β-[[(1,1-Dimethylethyl)Dimethylsilyl]Oxy]-α-Methyl- is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support compliance with ICH guidelines for impurities and can tailor specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.