Description

[1,2,4]Triazolo[1,5-A]Pyridine, 6-[1-[[(1,1-Dimethylethyl)Dimethylsilyl]Oxy]-2-Nitropropyl]- is a sophisticated, high-purity chemical intermediate featuring a protected hydroxyl group and a nitro functionality, making it a versatile building block for advanced synthesis. This compound is critical for research and development in pharmaceutical chemistry, where precise molecular architecture is required. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those containing the [1,2,4]triazolo[1,5-a]pyridine core, which is of interest in medicinal chemistry.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides that require specific heterocyclic structures for bioactivity.
• Organic Synthesis Reagent: Serves as a protected synthon in multi-step organic reactions, where the tert-butyldimethylsilyl (TBDMS) group allows for selective manipulation of other functional groups.
• Material Science Precursor: Potential intermediate in the development of organic electronic materials, dyes, and photoactive compounds.
• Academic & Contract Research: Essential for fundamental research in heterocyclic chemistry and methodology development within university and CRO (Contract Research Organization) laboratories.

Basic Information

Item	Details
Product Name	[1,2,4]Triazolo[1,5-A]Pyridine, 6-[1-[[(1,1-Dimethylethyl)Dimethylsilyl]Oxy]-2-Nitropropyl]-
CAS No.	1043907-95-4
Molecular Formula	C15H24N4O3Si
Molecular Weight	336.47 g/mol
Synonyms	6-[1-[(tert-Butyldimethylsilyl)oxy]-2-nitropropyl][1,2,4]triazolo[1,5-a]pyridine; 6-(1-((tert-Butyldimethylsilyl)oxy)-2-nitropropyl)-[1,2,4]triazolo[1,5-a]pyridine; TBDMS-protected nitropropyl triazolopyridine; (1,1-Dimethylethyl)[[2-nitro-1-(6-[1,2,4]triazolo[1,5-a]pyridinyl)propyl]oxy]dimethylsilane
EINECS	Contact for details

Quality Control

Our production of [1,2,4]Triazolo[1,5-A]Pyridine, 6-[1-[[(1,1-Dimethylethyl)Dimethylsilyl]Oxy]-2-Nitropropyl]- adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity, essential for sensitive synthetic applications. All materials are characterized by modern analytical techniques including NMR, HPLC, and MS. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.