Description

1-([1,2,4]Triazolo[1,5-A]Pyridin-6-Yl)-2-Nitropropan-1-Ol is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of novel active pharmaceutical ingredients (APIs). This compound matters for its role as a critical building block in modern medicinal chemistry, enabling the development of targeted therapeutics. It is primarily needed by research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in the discovery and production of innovative drugs, particularly in oncology and antiviral research.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new chemical entities (NCEs) and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Oncology Drug Development: Used in the synthesis of potential therapeutic agents targeting specific cancer pathways.
• Antiviral Agent Synthesis: Employed as a building block for creating novel compounds with potential antiviral activity.
• Chemical Biology Probes: Utilized in the development of specialized probes for studying biological processes and target identification.
• Contract Manufacturing: Supplied to CDMOs for scale-up synthesis under current Good Manufacturing Practice (cGMP) conditions for clinical trial material production.

Basic Information

Product Name	1-([1,2,4]Triazolo[1,5-A]Pyridin-6-Yl)-2-Nitropropan-1-Ol
CAS No.	1043907-94-3
Molecular Formula	C9H8N4O3
Molecular Weight	220.19 g/mol
Synonyms	1-([1,2,4]Triazolo[1,5-a]pyridin-6-yl)-2-nitro-1-propanol; 2-Nitro-1-([1,2,4]triazolo[1,5-a]pyridin-6-yl)propan-1-ol; 1-(1,2,4-Triazolo[1,5-a]pyridin-6-yl)-2-nitropropan-1-ol; 6-(1-Hydroxy-2-nitropropyl)[1,2,4]triazolo[1,5-a]pyridine; [1,2,4]Triazolo[1,5-a]pyridine-6-ethanol, β-nitro-
EINECS	Contact for details

Quality Control

Our 1-([1,2,4]Triazolo[1,5-A]Pyridin-6-Yl)-2-Nitropropan-1-Ol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided for each lot. We support development with research-grade material and can scale production under cGMP guidelines for advanced clinical stages.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single unknown impurity ≤ 1.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.