Description

Methyl 4-Bromonicotinate is a versatile brominated nicotinate ester, serving as a crucial building block in advanced organic synthesis. Its value lies in the strategic positioning of the bromine atom, which enables efficient cross-coupling reactions and functional group transformations. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients, particularly in the creation of complex heterocyclic compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Building block for developing new herbicides, fungicides, and insecticides with improved efficacy.
• Material Science Research: Used in the development of organic electronic materials, ligands for catalysis, and novel polymers.
• Cross-Coupling Reactions: Essential substrate for Suzuki, Stille, and Negishi couplings to form biaryl and other complex structures.
• Chemical Biology: Useful for synthesizing probes and labeled compounds for biochemical and pharmacological studies.
• Academic & R&D: Fundamental reagent in university and corporate research laboratories for methodological development and discovery chemistry.

Basic Information

Product Name	Methyl 4-Bromonicotinate
CAS No.	1043419-29-9
Molecular Formula	C7H6BrNO2
Molecular Weight	216.03 g/mol
Synonyms	4-Bromonicotinic Acid Methyl Ester; Methyl 4-Bromopyridine-3-carboxylate; 3-Pyridinecarboxylic Acid, 4-Bromo-, Methyl Ester; 4-Bromo-3-pyridinecarboxylic Acid Methyl Ester; 4-Bromonicotinic Acid, Methyl Ester; Methyl 4-Bromo-3-pyridinecarboxylate; 1043419-29-9
EINECS	Contact for details

Quality Control

Our Methyl 4-Bromonicotinate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from direct light to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.