Description

3,17-Estradiol-3-Methylether-17-Decanoate is a synthetic, lipophilic ester derivative of estradiol, designed for enhanced stability and controlled release profiles. This compound is significant for its role as a key pharmaceutical intermediate in the development of advanced hormone therapies and long-acting parenteral formulations. It is primarily required by manufacturers in the pharmaceutical, biotechnology, and advanced research sectors for the synthesis of novel steroidal active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel steroidal drugs and prodrugs.
• Hormone Replacement Therapy (HRT) Research: Used in the development of long-acting estrogen formulations with modified pharmacokinetics.
• Prodrug Development: Serves as a model compound for creating ester-based prodrugs to improve bioavailability and duration of action.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for method development and validation.
• Biochemical Research: Utilized in academic and industrial research to study estrogen receptor interactions and metabolic pathways.
• Veterinary Pharmaceuticals: Potential application in developing sustained-release hormonal treatments for animals.

Basic Information

Product Name	3,17-Estradiol-3-Methylether-17-Decanoate
CAS No.	1042947-85-2
Molecular Formula	C29H46O4
Molecular Weight	458.68 g/mol
Synonyms	Estradiol 3-Methyl Ether 17-Decanoate; 17β-Estradiol 3-Methyl Ether 17-Decanoate; Estrone 3-Methyl Ether 17-Decanoate Derivative; 3-Methoxyestra-1,3,5(10)-trien-17β-yl decanoate; Decanoic acid, (17β)-3-methoxyestra-1,3,5(10)-trien-17-yl ester; NSC 106679; 3,17-Estradiol dimethylether decanoate (related).
EINECS	Contact for details

Quality Control

Our 3,17-Estradiol-3-Methylether-17-Decanoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets exacting standards for pharmaceutical intermediate use. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Single Maximum Unknown Impurity	≤0.5%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.