Description

4-(6-Bromo-Pyridin-2-Ylamino)-Piperidine-1-Carboxylic Acid tert-Butyl Ester is a high-purity (98+%) advanced pharmaceutical intermediate with the molecular formula C15H22BrN3O2 and a molecular weight of 356.27. This compound is critical for medicinal chemistry research and development, serving as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of complex drug candidates, particularly those targeting neurological and oncological pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic agents.
• Process Chemistry Development: Serves as a standardized building block for scaling up synthetic routes under cGMP conditions.
• Library Synthesis: Employed in the generation of diverse compound libraries for high-throughput screening in drug discovery.
• Chemical Biology Probes: Used to create tool compounds for studying biological mechanisms and target validation.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke molecules for clients.

Basic Information

Item	Detail
Product Name	4-(6-Bromo-Pyridin-2-Ylamino)-Piperidine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	1042224-77-0
Molecular Formula	C15H22BrN3O2
Molecular Weight	356.27 g/mol
Synonyms	tert-Butyl 4-[(6-bromopyridin-2-yl)amino]piperidine-1-carboxylate; 1-Boc-4-[(6-bromo-2-pyridinyl)amino]piperidine; 4-[(6-Bromo-2-pyridinyl)amino]-1-piperidinecarboxylic acid 1,1-dimethylethyl ester; 1-(tert-Butoxycarbonyl)-4-[(6-bromopyridin-2-yl)amino]piperidine; 4-(6-Bromo-2-pyridinylamino)piperidine-1-carboxylic acid tert-butyl ester; Boc-4-(6-bromopyridin-2-ylamino)piperidine
EINECS	Contact for details

Quality Control

Our 4-(6-Bromo-Pyridin-2-Ylamino)-Piperidine-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure a purity of 98+% and compliance with stringent internal specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.