Description

3-Chloro-n-Cyclopentyl-5-(Trifluoromethyl)Pyridin-2-Amine is a high-value, multi-functional heterocyclic building block featuring a pyridine core substituted with chloro, cyclopentylamino, and trifluoromethyl groups. This compound is engineered to serve as a critical intermediate in advanced organic synthesis, offering significant utility in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. Its unique structure makes it particularly valuable for medicinal chemistry research and process development within the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) therapeutic research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the pyridine and trifluoromethyl motifs.
• Material Science Research: Serves as a precursor for creating functionalized ligands and complex organic molecules used in catalysis and advanced materials.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in client-specific R&D and scale-up projects.

Basic Information

Product Name	3-Chloro-n-Cyclopentyl-5-(Trifluoromethyl)Pyridin-2-Amine
CAS No.	1041581-59-2
Molecular Formula	C11H12ClF3N2
Molecular Weight	264.67 g/mol
Synonyms	3-Chloro-N-cyclopentyl-5-(trifluoromethyl)pyridin-2-amine; 2-Pyridinamine, 3-chloro-N-cyclopentyl-5-(trifluoromethyl)-; 3-Chloro-N-cyclopentyl-5-(trifluoromethyl)-2-pyridinamine; 1041581-59-2; 3-Chloro-5-trifluoromethyl-N-cyclopentylpyridin-2-amine
EINECS	Contact for details

Quality Control

Our production of 3-Chloro-n-Cyclopentyl-5-(Trifluoromethyl)Pyridin-2-Amine adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is fully characterized and tested using advanced analytical techniques including HPLC, GC, NMR, and MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Any single impurity ≤ 1.0%; Total impurities ≤ 3.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5% w/w

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.