Description

(R)-2,2',3,3'-Tetrahydro-1,1'-Spirobi[1H-Indene]-7,7'-Diamine is a high-purity chiral diamine building block of significant interest in advanced organic synthesis. This compound matters for its role as a key precursor in the development of chiral ligands, catalysts, and active pharmaceutical ingredients (APIs), where its specific stereochemistry is critical for function. It is needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors focused on asymmetric synthesis and molecular recognition.

Application

• As a chiral scaffold for the synthesis of novel asymmetric catalysts and ligands used in enantioselective transformations.
• Critical intermediate in the research and development of pharmaceutical candidates, particularly for central nervous system (CNS) targets.
• Building block for constructing complex macrocyclic compounds and molecular cages with specific host-guest properties.
• Precursor in the synthesis of advanced polymeric materials and dendrimers with tailored optical or mechanical characteristics.
• Starting material for agrochemical research, enabling the creation of enantiomerically pure active ingredients.
• Use in academic research to study stereochemistry, reaction mechanisms, and new synthetic methodologies.

Basic Information

Product Name	(R)-2,2',3,3'-Tetrahydro-1,1'-Spirobi[1H-Indene]-7,7'-Diamine
CAS No.	1041434-65-4
Molecular Formula	C17H18N2
Molecular Weight	250.34 g/mol
Synonyms	(R)-Spirobiindane-7,7'-diamine; (7R)-7,7'-Diamino-2,2',3,3'-tetrahydro-1,1'-spirobi[indene]; (R)-7,7'-Diamino-2,2',3,3'-tetrahydro-1,1'-spirobi[1H-indene]; (R)-Spiro[1H-indene-1,1'-indene]-7,7'-diamine, 2,2',3,3'-tetrahydro-, (7R)-; (R)-SBI-Diamine; (R)-SpiroBI-DA
EINECS	Contact for details

Quality Control

Our (R)-2,2',3,3'-Tetrahydro-1,1'-Spirobi[1H-Indene]-7,7'-Diamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high chemical and enantiomeric purity suitable for demanding synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.