Description

1H-Pyrazol-3-Amine, 5-[6-(Trifluoromethyl)-3-Pyridinyl]- is a high-purity, heterocyclic organic compound featuring a pyrazole core substituted with an amino group and a trifluoromethylpyridinyl moiety. This structure makes it a versatile and valuable building block for advanced chemical synthesis, particularly in the development of novel active ingredients. It is primarily sought after by pharmaceutical and agrochemical research & development teams for creating new drug candidates and crop protection agents.

Application

This specialized pyrazole derivative serves as a critical intermediate in sophisticated organic synthesis. Its primary applications include:

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the biological activity of the pyrazole and trifluoromethylpyridine motifs.
• Material Science: Employed in the research and synthesis of advanced organic materials, such as ligands for catalysts or components for electronic materials.
• Chemical Biology: Acts as a scaffold or probe in medicinal chemistry for structure-activity relationship (SAR) studies and hit-to-lead optimization.

Basic Information

Product Name	1H-Pyrazol-3-Amine, 5-[6-(Trifluoromethyl)-3-Pyridinyl]-
CAS No.	1040724-49-9
Molecular Formula	C9H7F3N4
Molecular Weight	228.18 g/mol
Synonyms	5-[6-(Trifluoromethyl)pyridin-3-yl]-1H-pyrazol-3-amine; 3-Amino-5-(6-(trifluoromethyl)pyridin-3-yl)-1H-pyrazole; 5-(6-(Trifluoromethyl)-3-pyridinyl)-1H-pyrazol-3-amine; 1040724-49-9; 5-(6-(Trifluoromethyl)pyridin-3-yl)-1H-pyrazol-3-amine
EINECS	Contact for details

Quality Control

We maintain a stringent quality management system to ensure the consistency and purity of our advanced intermediates. Every batch of 1H-Pyrazol-3-Amine, 5-[6-(Trifluoromethyl)-3-Pyridinyl]- is analyzed using advanced techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.