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4-{2-Methyl-6-[(2-Methylprop-2-En-1-Yl)Oxy]-4-Oxoquinazolin-3(4H)-Yl}-n-(Pyridin-4-Ylmethyl)Benzamide CAS NO 1040706-65-7


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CAS No.:1040706-65-7

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

4-{2-Methyl-6-[(2-Methylprop-2-En-1-Yl)Oxy]-4-Oxoquinazolin-3(4H)-Yl}-n-(Pyridin-4-Ylmethyl)Benzamide is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a key building block in the research and development of novel therapeutic agents, particularly in oncology and targeted drug discovery. It is essential for pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in synthesizing next-generation small molecule drugs.

Application

  • Pharmaceutical Intermediate: A critical precursor in the synthesis of targeted kinase inhibitors and other biologically active molecules.
  • Oncology Research: Used in the development and optimization of novel anti-cancer drug candidates targeting specific cellular pathways.
  • Medicinal Chemistry: Serves as a sophisticated scaffold for structure-activity relationship (SAR) studies and lead compound optimization.
  • Biochemical Research: Employed as a tool compound in enzymatic assays and target validation studies within academic and industrial research settings.
  • Custom Synthesis: A starting material for the contract manufacturing of high-value, non-commercial APIs for clinical trials.

Basic Information

Product Name 4-{2-Methyl-6-[(2-Methylprop-2-En-1-Yl)Oxy]-4-Oxoquinazolin-3(4H)-Yl}-n-(Pyridin-4-Ylmethyl)Benzamide
CAS No. 1040706-65-7
Molecular Formula C26H24N4O3
Molecular Weight 440.50 g/mol
Synonyms 4-(2-Methyl-6-((2-methylallyl)oxy)-4-oxoquinazolin-3(4H)-yl)-N-(pyridin-4-ylmethyl)benzamide; 4-[2-Methyl-6-(2-methylprop-2-en-1-yloxy)-4-oxoquinazolin-3(4H)-yl]-N-(pyridin-4-ylmethyl)benzamide; Benzamide, 4-[2-methyl-6-[(2-methyl-2-propen-1-yl)oxy]-4-oxo-3(4H)-quinazolinyl]-N-(4-pyridinylmethyl)-; 1040706-65-7; UNII-8J8Q8Y8F7I; 8J8Q8Y8F7I
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Quality Control

Our 4-{2-Methyl-6-[(2-Methylprop-2-En-1-Yl)Oxy]-4-Oxoquinazolin-3(4H)-Yl}-n-(Pyridin-4-Ylmethyl)Benzamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) detailing purity, impurities, and other critical parameters are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Identification (HPLC) Retention time matches reference standard
Purity (HPLC) ≥ 98.0%
Related Substances (HPLC) Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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