Description

3-Fluoro-2-Hydroxy-5-(Trifluoromethyl)Pyridine is a high-value, multi-fluorinated pyridine derivative that serves as a critical building block in advanced chemical synthesis. Its unique structure, featuring both fluorine and a trifluoromethyl group on the pyridine ring, makes it an essential intermediate for creating compounds with enhanced biological activity and specific physicochemical properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in areas like kinase inhibitors and central nervous system (CNS) agents.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides, where the fluorine atoms contribute to improved metabolic stability and bioavailability.
• Material Science Precursor: Serves as a building block for specialty chemicals, including liquid crystals and organic electronic materials.
• Chemical Research & Development: Employed in academic and industrial R&D labs for exploring new fluorination chemistry and constructing complex heterocyclic scaffolds.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of tailored compounds for client projects.

Basic Information

Product Name	3-Fluoro-2-Hydroxy-5-(Trifluoromethyl)Pyridine
CAS No.	1040683-15-5
Molecular Formula	C6H3F4NO
Molecular Weight	181.09 g/mol
Synonyms	5-(Trifluoromethyl)-3-fluoro-2-pyridinol; 3-Fluoro-5-(trifluoromethyl)pyridin-2-ol; 2-Hydroxy-3-fluoro-5-(trifluoromethyl)pyridine; 3-Fluoro-2-hydroxy-5-trifluoromethylpyridine; 2-Pyridinol, 3-fluoro-5-(trifluoromethyl)-; 1040683-15-5; 3-Fluoro-5-trifluoromethyl-2-pyridone (tautomeric form)
EINECS	Contact for details

Quality Control

Every batch of 3-Fluoro-2-Hydroxy-5-(Trifluoromethyl)Pyridine is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee compliance with your research and production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and oxidizing agents. For long-term storage, consider an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.