Description

tert-Butyl 4-(2-(Trifluoromethyl)-1,6-Naphthyridin-5-Ylamino)Piperidine-1-Carboxy is a high-purity, advanced pharmaceutical intermediate designed for research and development. This compound is critical for medicinal chemists working on novel drug candidates, particularly in oncology and other therapeutic areas. Its primary value lies in its role as a key building block for synthesizing complex molecules with potential biological activity. This product is essential for pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers focused on developing next-generation therapeutics.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of novel active pharmaceutical ingredients (APIs) and drug candidates.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic agents.
• Oncology Drug Development: A key precursor in the synthesis of targeted cancer therapies, leveraging the 1,6-naphthyridine scaffold.
• Kinase Inhibitor Synthesis: Employed in the development of small molecule inhibitors targeting specific kinase pathways.
• Process Chemistry & Scale-up: Used for route scouting and process optimization from milligram to kilogram scale in fine chemical production.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	tert-Butyl 4-(2-(Trifluoromethyl)-1,6-Naphthyridin-5-Ylamino)Piperidine-1-Carboxy
CAS No.	1040682-38-9
Molecular Formula	C19H23F3N4O2
Molecular Weight	396.41 g/mol
Synonyms	1,1-Dimethylethyl 4-[[2-(trifluoromethyl)-1,6-naphthyridin-5-yl]amino]-1-piperidinecarboxylate; tert-Butyl 4-((2-(trifluoromethyl)-1,6-naphthyridin-5-yl)amino)piperidine-1-carboxylate; 1-Boc-4-((2-(trifluoromethyl)-1,6-naphthyridin-5-yl)amino)piperidine; 1040682-38-9; 5-((1-(tert-Butoxycarbonyl)piperidin-4-yl)amino)-2-(trifluoromethyl)-1,6-naphthyridine
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(2-(Trifluoromethyl)-1,6-Naphthyridin-5-Ylamino)Piperidine-1-Carboxy is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring the material meets the stringent requirements for pharmaceutical R&D and pre-clinical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.