Description

2-Fluoro-4-(Trifluoromethyl)Pyridine-3-Carboxylicacid is a high-value fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both fluorine and a trifluoromethyl group, is engineered to impart desirable properties such as metabolic stability and enhanced lipophilicity to target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing next-generation active ingredients. The CAS number for this compound is 1040681-74-0.

Application

This fluorinated pyridine carboxylic acid is a versatile intermediate designed for sophisticated chemical synthesis. Its primary applications include:

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, oncology, and inflammatory diseases.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, where the fluorine atoms contribute to biological activity and environmental persistence.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in catalysis and molecular recognition processes.
• Material Science Research: Employed in the development of advanced organic materials, such as liquid crystals or polymers with specific electronic properties.
• Custom Synthesis and Contract Manufacturing: A valuable scaffold for medicinal chemistry and process research organizations (CROs/CMOs) engaged in custom synthesis projects.

Basic Information

Product Name	2-Fluoro-4-(Trifluoromethyl)Pyridine-3-Carboxylicacid
CAS No.	1040681-74-0
Molecular Formula	C7H3F4NO2
Molecular Weight	209.10 g/mol
Synonyms	2-Fluoro-4-(trifluoromethyl)nicotinic acid; 3-Pyridinecarboxylic acid, 2-fluoro-4-(trifluoromethyl)-; 2-Fluoro-4-trifluoromethylpyridine-3-carboxylic acid; 1040681-74-0; 2-Fluoro-4-(trifluoromethyl)pyridine-3-carboxylic acid
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for our fluorinated intermediates. Production follows cGMP principles where applicable, and every batch is analyzed using advanced techniques like HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. For long-term storage, we recommend keeping the product at 2-8°C under an inert atmosphere to maintain stability. The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.