Description

1-(4-(3-Aminopyridin-4-Yl)Piperazin-1-Yl)Ethanone is a high-purity, advanced pharmaceutical intermediate featuring a unique pyridine-piperazine-acetamide scaffold. This compound is of significant commercial interest for its role as a key building block in the synthesis of novel bioactive molecules. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of targeted therapeutics, particularly within oncology and central nervous system (CNS) drug discovery pipelines.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of small-molecule drug candidates targeting specific protein kinases and receptors.
• Medicinal Chemistry Research: Serves as a versatile scaffold for constructing compound libraries in high-throughput screening (HTS) and structure-activity relationship (SAR) studies.
• Oncology Drug Development: Used in the R&D of potential inhibitors for cancer-related enzymatic pathways.
• CNS-Active Compound Synthesis: Employed in creating novel molecules intended for neurological and psychiatric disorder treatments.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting global drug discovery programs.
• Academic Research: Utilized in university and institutional labs for fundamental chemical biology and pharmacology studies.

Basic Information

Product Name	1-(4-(3-Aminopyridin-4-Yl)Piperazin-1-Yl)Ethanone
CAS No.	1039971-85-1
Molecular Formula	C11H15N5O
Molecular Weight	233.27 g/mol
Synonyms	1-[4-(3-Aminopyridin-4-yl)piperazin-1-yl]ethanone; 1-[4-(3-Amino-4-pyridinyl)-1-piperazinyl]ethanone; 4-(4-Acetylpiperazin-1-yl)pyridin-3-amine; 3-Amino-4-(4-acetylpiperazin-1-yl)pyridine; 1039971-85-1; Ethanone, 1-[4-(3-amino-4-pyridinyl)-1-piperazinyl]-; AKOS025147193
EINECS	Contact for details

Quality Control

Our 1-(4-(3-Aminopyridin-4-Yl)Piperazin-1-Yl)Ethanone is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with client specifications and relevant ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.