Description

Methyl 2-(Chlorosulfonyl)-5-Nitrobenzoate is a versatile and high-value organic synthesis intermediate characterized by its reactive chlorosulfonyl and ester functional groups. This compound is critical for the efficient construction of complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and advanced agrochemicals. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing sulfonamide-based compounds and other fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel sulfonamide-containing drug candidates, including potential enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the sulfonamide moiety imparts biological activity.
• Dye and Pigment Manufacturing: Serves as a precursor for synthesizing specialized azo dyes and pigments that require nitro and sulfonyl chloride functionalities.
• Polymer Science: Can be utilized to create functional monomers or cross-linking agents for specialty polymers with tailored properties.
• Chemical Research & Development: An essential reagent in academic and industrial labs for methodological studies in organic synthesis and heterocyclic chemistry.
• Material Science: Potential use in the development of advanced organic materials, such as organic semiconductors or metal-organic frameworks (MOFs).

Basic Information

Product Name	Methyl 2-(Chlorosulfonyl)-5-Nitrobenzoate
CAS No.	1039020-81-9
Molecular Formula	C8H6ClNO6S
Molecular Weight	279.65 g/mol
Synonyms	5-Nitro-2-(chlorosulfonyl)benzoic acid methyl ester; Methyl 5-nitro-2-(chlorosulfonyl)benzoate; 2-(Chlorosulfonyl)-5-nitrobenzoic acid methyl ester; Benzoic acid, 2-(chlorosulfonyl)-5-nitro-, methyl ester; Methyl 2-chlorosulfonyl-5-nitrobenzoate
EINECS	Contact for details

Quality Control

Every batch of Methyl 2-(Chlorosulfonyl)-5-Nitrobenzoate is produced and tested under strict quality management protocols to ensure consistency and reliability for your synthetic processes. We employ advanced analytical techniques, including HPLC, NMR, and IR spectroscopy, to verify identity, purity, and the absence of critical impurities. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment, and we support custom purity requirements for specific R&D or cGMP applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Recommended long-term storage temperature is 2-8°C. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.