Description

3-(2,2,2-Trifluoroethoxy)Pyridin-2-Amine is a high-purity, specialized pyridine derivative featuring a trifluoroethoxy substituent, making it a valuable fluorinated building block for advanced chemical synthesis. This compound is critical for researchers and manufacturers requiring precise molecular modifications to enhance the properties of target molecules. It is primarily utilized in the development of active pharmaceutical ingredients (APIs), agrochemicals, and functional materials where the introduction of fluorine can dramatically alter bioavailability, stability, and activity.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and insecticides where the trifluoroethoxy group contributes to improved lipophilicity and metabolic resistance.
• Material Science Research: Serves as a precursor for fluorinated ligands, liquid crystals, and polymers that require specific electronic or surface properties.
• Chemical Biology Probes: Employed in the design of fluorinated probes and tags for studying biological mechanisms and diagnostic applications.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects requiring high-purity fluorinated intermediates.

Basic Information

Product Name	3-(2,2,2-Trifluoroethoxy)Pyridin-2-Amine
CAS No.	1037160-20-5
Molecular Formula	C7H7F3N2O
Molecular Weight	192.14 g/mol
Synonyms	2-Amino-3-(2,2,2-trifluoroethoxy)pyridine; 3-(2,2,2-Trifluoroethoxy)-2-pyridinamine; 2-Pyridinamine, 3-(2,2,2-trifluoroethoxy)-; 1037160-20-5; 3-(Trifluoroethoxy)pyridin-2-amine
EINECS	Contact for details

Quality Control

Our production of 3-(2,2,2-Trifluoroethoxy)Pyridin-2-Amine adheres to stringent quality management protocols. Each batch is manufactured under controlled conditions and undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical quality attributes are provided with every shipment. We support cGMP (current Good Manufacturing Practice) standards for applications requiring the highest level of quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.