Description

Methyl 4-(2,6-Difluorophenyl)-2,4-Dioxobutanoate is a high-purity, specialized organic building block featuring a difluorophenyl-substituted dioxobutanoate structure. This compound is valued for its role as a critical synthetic intermediate in the development of advanced pharmaceutical and agrochemical active ingredients. It is primarily sought by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and crop protection industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Serves as a vital building block for developing next-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the difluorophenyl moiety.
• Chemical Research & Development: Used in academic and industrial R&D labs for method development, scaffold hopping, and exploring new chemical spaces in medicinal chemistry.
• Material Science Precursor: Potential intermediate for synthesizing specialized monomers or ligands used in advanced polymeric materials and catalysts.

Basic Information

Product Name	Methyl 4-(2,6-Difluorophenyl)-2,4-Dioxobutanoate
CAS No.	1037130-74-7
Molecular Formula	C11H8F2O4
Molecular Weight	242.18 g/mol
Synonyms	Methyl 4-(2,6-difluorophenyl)-2,4-dioxobutanoate; 4-(2,6-Difluorophenyl)-2,4-dioxobutanoic Acid Methyl Ester; 2,4-Dioxo-4-(2,6-difluorophenyl)butanoic Acid Methyl Ester; Methyl 4-(2,6-difluorobenzoyl)acetoacetate; 1037130-74-7; Butanoic acid, 4-(2,6-difluorophenyl)-2,4-dioxo-, methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 4-(2,6-Difluorophenyl)-2,4-Dioxobutanoate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the stringent requirements for advanced synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.