Description

Imidazo[1,2-A]Pyridine-7-Carbonitrile, 3-Iodo- is a high-value, halogenated heterocyclic building block of significant interest in advanced organic synthesis. Its core structure, featuring both an imidazopyridine scaffold and a reactive cyano group, makes it a versatile precursor for constructing complex molecular architectures. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries. It serves as a critical intermediate for the development of new active ingredients, particularly in medicinal chemistry programs targeting novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in the development of kinase inhibitors, antiviral agents, and other biologically active small molecules.
• Agrochemical Research: Used in the discovery and synthesis of new herbicides, fungicides, and insecticides, leveraging its heterocyclic core for bioactivity.
• Material Science Precursor: Serves as a starting material for the creation of specialized organic ligands, dyes, and functional polymers with tailored electronic properties.
• Chemical Biology Probe Development: Employed in the design and synthesis of molecular probes and tags for studying biological systems and mechanisms.
• Cross-Coupling Reactions: The iodine substituent makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to create diverse compound libraries.
• Academic & Contract Research: Essential for fundamental research in organic methodology and heterocyclic chemistry within universities and CROs (Contract Research Organizations).

Basic Information

Item	Detail
Product Name	Imidazo[1,2-A]Pyridine-7-Carbonitrile, 3-Iodo-
CAS No.	1036990-70-1
Molecular Formula	C8H4IN3
Molecular Weight	269.04 g/mol
Synonyms	3-Iodoimidazo[1,2-a]pyridine-7-carbonitrile; 3-Iodo-7-cyanoimidazo[1,2-a]pyridine; 7-Cyano-3-iodoimidazo[1,2-a]pyridine; Imidazo[1,2-a]pyridine-7-carbonitrile, 3-iodo-; 1036990-70-1; 3-Iodo-7-imidazo[1,2-a]pyridinecarbonitrile
EINECS	Contact for details

Quality Control

Our Imidazo[1,2-A]Pyridine-7-Carbonitrile, 3-Iodo- is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure consistency and compliance with research-grade specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). This material is light-sensitive (store away from light). Keep container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.