Description

2-[(2,2-Dimethylpropanoyl)Amino]Pyridin-3-Boronic Acid is a specialized boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its value lies in its dual functionality, combining a protected amino group with a boronic acid moiety, enabling precise cross-coupling reactions for complex molecule assembly. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs) and advanced materials through Suzuki-Miyaura coupling.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially in oncology and central nervous system (CNS) therapeutic areas.
• Suzuki-Miyaura Cross-Coupling Reagent: Used as a versatile coupling partner with aryl halides to form biaryl and heterobiaryl structures, a cornerstone reaction in medicinal chemistry.
• Agrochemical Synthesis: Employed in the research and development of new-generation herbicides and fungicides with improved efficacy.
• Material Science Research: Facilitates the creation of organic electronic materials, such as those used in OLEDs and organic photovoltaics.
• Chemical Biology Probes: Useful in constructing molecular probes for studying enzyme activity and protein-ligand interactions.
• Custom Synthesis & Contract Manufacturing: Serves as a high-value starting material for custom synthesis projects and scale-up processes under cGMP conditions.

Basic Information

Product Name	2-[(2,2-Dimethylpropanoyl)Amino]Pyridin-3-Boronic Acid
CAS No.	1036243-43-2
Molecular Formula	C12H17BN2O3
Molecular Weight	248.09 g/mol
Synonyms	3-Pyridineboronic acid, 2-[(2,2-dimethyl-1-oxopropoxy)amino]-; 2-(Pivalamido)pyridine-3-boronic acid; 2-(Pivaloylamino)pyridin-3-ylboronic acid; N-(3-Boronopyridin-2-yl)pivalamide; 2-Aminopyridin-3-boronic acid pivalate; 1036243-43-2; Boronic acid, B-[2-[(2,2-dimethyl-1-oxopropoxy)amino]-3-pyridinyl]-; B-[2-(Pivaloylamino)-3-pyridyl]boronic acid
EINECS	Contact for details

Quality Control

Every batch of 2-[(2,2-Dimethylpropanoyl)Amino]Pyridin-3-Boronic Acid is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive coupling reactions and regulatory filings. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profiles via validated methods such as HPLC, NMR, and elemental analysis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.