Description

3-(6-Bromopyridin-3-Yl)Propanoic Acid is a high-purity brominated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in providing a versatile carboxylic acid handle adjacent to a halogenated heterocyclic core, enabling precise molecular construction. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of small molecule drug candidates, particularly kinase inhibitors and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Building block for developing new herbicides, fungicides, and insecticides with tailored activity profiles.
• Ligand and Catalyst Development: Used to create novel pyridine-based ligands for transition metal catalysis and coordination chemistry.
• Material Science Research: Monomer or functionalizing agent in the development of specialty polymers and organic electronic materials.
• Chemical Biology Probes: Serves as a starting point for synthesizing molecular probes and biochemical tools for target identification and validation.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research organizations for bespoke synthesis projects and scale-up campaigns.

Basic Information

Product Name	3-(6-Bromopyridin-3-Yl)Propanoic Acid
CAS No.	1036227-86-7
Molecular Formula	C8H8BrNO2
Molecular Weight	230.06 g/mol
Synonyms	3-(6-Bromo-3-pyridinyl)propanoic Acid; 6-Bromo-3-pyridinepropanoic Acid; 3-(6-Bromopyridin-3-yl)propionic Acid; 3-(6-Bromo-3-pyridyl)propanoic Acid; β-(6-Bromo-3-pyridyl)propionic Acid; 1036227-86-7 (CAS); 3-(6-Bromopyridin-3-Yl)Propanoic Acid
EINECS	Contact for details

Quality Control

Our 3-(6-Bromopyridin-3-Yl)Propanoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if possible to prevent degradation. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Area Percent)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.