Description

1-(2-Chloro-3-Methylpyridin-4-Yl)Ethanone is a high-purity, synthetically valuable pyridine derivative. This compound serves as a critical advanced pharmaceutical intermediate and a versatile building block in organic synthesis. It is primarily needed by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly those targeting the central nervous system or acting as kinase inhibitors.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core.
• Ligand and Catalyst Development: Serves as a starting material for creating novel ligands used in catalytic processes and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic electronic materials and functional dyes due to its electron-deficient aromatic system.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthetic routes.
• Academic and Industrial R&D: Used in research laboratories for methodological studies and exploring new chemical reactions.

Basic Information

Product Name	1-(2-Chloro-3-Methylpyridin-4-Yl)Ethanone
CAS No.	1035946-00-9
Molecular Formula	C8H8ClNO
Molecular Weight	169.61 g/mol
Synonyms	4-Acetyl-2-chloro-3-methylpyridine; 2-Chloro-3-methyl-4-acetylpyridine; 1-(2-Chloro-3-methyl-4-pyridinyl)ethanone; 2-Chloro-3-methylpyridin-4-yl methyl ketone; 4-Acetyl-2-chloro-3-picoline; Ethanone, 1-(2-chloro-3-methyl-4-pyridinyl)-; 2-Chloro-3-methyl-4-pyridyl methyl ketone
EINECS	Contact for details

Quality Control

Our 1-(2-Chloro-3-Methylpyridin-4-Yl)Ethanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring GMP-grade intermediates and high-purity research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.