Description

3-Pyridin-4-Yl-Pyrazolo[1,5-A]Pyrimidine-6-Carbaldehyde is a high-purity heterocyclic aldehyde building block of significant interest in advanced organic synthesis. Its core value lies in its versatile reactivity, serving as a key precursor for constructing complex molecular architectures, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists working on novel active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and other targeted therapy research.
• Medicinal Chemistry: Used in lead optimization and structure-activity relationship (SAR) studies due to its reactive aldehyde group and fused pyrazolopyrimidine-pyridine scaffold.
• Chemical Biology: Employed in the development of molecular probes and tool compounds for studying biological pathways and target engagement.
• Agrochemical Research: Serves as a precursor in the development of new active ingredients for crop protection products.
• Material Science: Potential use as a monomer or functionalizing agent in the synthesis of specialty polymers and advanced organic materials.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) conducting cutting-edge synthetic chemistry projects.

Basic Information

Product Name	3-Pyridin-4-Yl-Pyrazolo[1,5-A]Pyrimidine-6-Carbaldehyde
CAS No.	1035818-93-9
Molecular Formula	C12H8N4O
Molecular Weight	224.22 g/mol
Synonyms	3-(Pyridin-4-yl)pyrazolo[1,5-a]pyrimidine-6-carbaldehyde; 3-(4-Pyridinyl)pyrazolo[1,5-a]pyrimidine-6-carboxaldehyde; Pyrazolo[1,5-a]pyrimidine-6-carbaldehyde, 3-(4-pyridinyl)-; 1035818-93-9; 4-(6-Formylpyrazolo[1,5-a]pyrimidin-3-yl)pyridine
EINECS	Contact for details

Quality Control

Our 3-Pyridin-4-Yl-Pyrazolo[1,5-A]Pyrimidine-6-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to quality supports compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. Due to its sensitivity to oxidation and light, prolonged exposure to air or light should be avoided.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.