Description

2-(3-(Difluoromethoxy)Phenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a high-purity boronic ester derivative, a critical building block in modern synthetic organic chemistry. Its primary value lies in its role as a versatile intermediate in cross-coupling reactions, enabling the efficient construction of complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality reagents for drug discovery and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, leveraging the difluoromethoxy phenyl moiety for enhanced biological activity.
• Liquid Crystal & OLED Materials: Serves as a building block for creating complex organic molecules used in electronic displays and optoelectronic devices.
• Polymer Chemistry: Employed in the synthesis of specialty polymers and functional materials with tailored properties.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D labs exploring new synthetic methodologies and compound libraries.
• Custom Synthesis: Used by fine chemical manufacturers for the contract production of bespoke organic compounds for various industries.

Basic Information

Product Name	2-(3-(Difluoromethoxy)Phenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	1035690-56-2
Molecular Formula	C₁₃H₁₇BF₂O₃
Molecular Weight	282.08 g/mol
Synonyms	3-(Difluoromethoxy)phenylboronic acid pinacol ester; (3-(Difluoromethoxy)phenyl)boronic acid pinacol ester; Pinacol [3-(difluoromethoxy)phenyl]boronate; [3-(Difluoromethoxyphenyl)]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 3-Difluoromethoxyphenylboronic Acid Pinacol Ester; B-[3-(Difluoromethoxy)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Our 2-(3-(Difluoromethoxy)Phenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC analysis, to ensure high purity and consistency suitable for sensitive cross-coupling reactions. Certificates of Analysis (COA) with detailed specifications are provided for each shipment, supporting compliance with cGMP and ISO standards for research and production use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Typical: 98-99%)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.