Description

Methyl 2-Chloro-5-Cyclopropylnicotinate CAS NO 1035690-30-2 is a high-purity, advanced pharmaceutical intermediate characterized by its cyclopropyl-substituted nicotinate core structure. This compound is a critical building block in modern medicinal chemistry, enabling the synthesis of novel active pharmaceutical ingredients (APIs) with targeted therapeutic effects. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the development of next-generation drugs and crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of complex drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Research: Serves as a precursor in developing novel pesticides and herbicides with specific modes of action.
• Chemical Synthesis: Used in organic synthesis for constructing complex heterocyclic frameworks and functionalized pyridine derivatives.
• Material Science: Potential building block for specialty chemicals and functional materials requiring specific molecular architectures.
• Contract Research & Manufacturing (CRAM): Supplied to CROs and CDMOs for custom synthesis and process development projects.

Basic Information

Product Name	Methyl 2-Chloro-5-Cyclopropylnicotinate
CAS No.	1035690-30-2
Molecular Formula	C10H10ClNO2
Molecular Weight	211.65 g/mol
Synonyms	Methyl 2-chloro-5-cyclopropylpyridine-3-carboxylate; 2-Chloro-5-cyclopropylnicotinic acid methyl ester; 3-Pyridinecarboxylic acid, 2-chloro-5-cyclopropyl-, methyl ester; 1035690-30-2; Methyl 2-chloro-5-cyclopropyl-3-pyridinecarboxylate; 5-Cyclopropyl-2-chloronicotinic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 2-Chloro-5-Cyclopropylnicotinate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specifications and test results. Our quality commitment ensures the material meets the stringent requirements for pharmaceutical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.