Description

5-Cyclopropyl-2-Fluoro-4-Iodopyridine is a high-purity, multi-functional halogenated pyridine derivative designed for advanced chemical synthesis. This compound serves as a critical building block in pharmaceutical and agrochemical research, enabling the construction of complex molecular architectures. It is primarily utilized by R&D chemists and process development scientists in the life sciences sector for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the bioactivity of the cyclopropyl and halogen substituents.
• Material Science: Serves as a monomer or functionalizing agent in the creation of specialty polymers and liquid crystals with unique electronic properties.
• Cross-Coupling Reactions: The iodine moiety makes it an excellent substrate for Suzuki-Miyaura, Stille, and Negishi cross-coupling reactions to form new carbon-carbon bonds.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies and library synthesis for drug discovery programs.
• Chemical Biology: Used as a probe or tag in biochemical assays due to its distinct halogen label.

Basic Information

Item	Detail
Product Name	5-Cyclopropyl-2-Fluoro-4-Iodopyridine
CAS No.	1034467-84-9
Molecular Formula	C8H7FIN
Molecular Weight	263.05 g/mol
Synonyms	5-Cyclopropyl-2-fluoro-4-iodopyridine; 2-Fluoro-4-iodo-5-cyclopropylpyridine; 4-Iodo-5-cyclopropyl-2-fluoropyridine; 1034467-84-9; 5-Cyclopropyl-4-iodo-2-fluoropyridine; 2-Fluoro-5-cyclopropyl-4-iodopyridine; 4-Iodo-2-fluoro-5-cyclopropylpyridine; Pyridine, 5-cyclopropyl-2-fluoro-4-iodo-
EINECS	Contact for details

Quality Control

Our 5-Cyclopropyl-2-Fluoro-4-Iodopyridine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and industry best practices for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.