Description

6-Methoxypyridine-2-Boronic Acid Pinacol Ester is a high-purity, protected boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex heterocyclic scaffolds. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for the development of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key reagent in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly those containing pyridine and methoxypyridine motifs.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides requiring specific heterocyclic structures.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands and organometallic catalysts used in asymmetric synthesis.
• Material Science Research: Building block for constructing organic electronic materials, such as those used in OLEDs and organic semiconductors.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes and tags for studying biological systems and target engagement.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and fine chemical producers for custom synthesis projects requiring high-fidelity coupling partners.

Basic Information

Product Name	6-Methoxypyridine-2-Boronic Acid Pinacol Ester
CAS No.	1034297-69-2
Molecular Formula	C₁₃H₂₀BNO₃
Molecular Weight	249.12 g/mol
Synonyms	2-(6-Methoxypyridin-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 6-Methoxy-2-pyridineboronic acid pinacol ester; 6-Methoxypyridine-2-boronic acid neopentyl glycol ester (common name); 2-(6-Methoxypyridin-2-yl)-1,3,2-dioxaborinane (alternative protected form); 6-Methoxy-2-pyridylboronic acid pinacol ester; Pinacol (6-methoxypyridin-2-yl)boronate; B-(6-Methoxy-2-pyridinyl)boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Every batch of 6-Methoxypyridine-2-Boronic Acid Pinacol Ester is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure consistency and high purity. Our standard grade meets the exacting requirements for research and process development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles by HPLC, NMR, and other relevant methods is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Purity (HPLC, Area%)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.