Description

2-Chloro-3-Iodo-4-Pyridinecarboxylic Acid Ethyl Ester is a high-value halogenated pyridine derivative, a crucial building block in advanced organic synthesis. Its unique substitution pattern makes it an indispensable intermediate for constructing complex molecules, particularly in pharmaceutical research and development. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides due to its bioactive pyridine core.
• Ligand Synthesis: Serves as a starting material for creating sophisticated ligands in catalysis and coordination chemistry.
• Material Science: Building block for functionalized polymers and advanced organic electronic materials.
• Cross-Coupling Reactions: The iodine and chlorine substituents make it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions.
• Chemical Library Development: Used in combinatorial chemistry and high-throughput screening for drug discovery programs.

Basic Information

Product Name	2-Chloro-3-Iodo-4-Pyridinecarboxylic Acid Ethyl Ester
CAS No.	1034132-14-3
Molecular Formula	C8H7ClINO2
Molecular Weight	311.51 g/mol
Synonyms	Ethyl 2-Chloro-3-iodopyridine-4-carboxylate; 4-Pyridinecarboxylic acid, 2-chloro-3-iodo-, ethyl ester; 2-Chloro-3-iodoisonicotinic acid ethyl ester; Ethyl 2-chloro-3-iodoisonicotinate; 2-Chloro-3-iodopyridine-4-carboxylic acid ethyl ester; 1034132-14-3
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-3-Iodo-4-Pyridinecarboxylic Acid Ethyl Ester is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for research and development. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for all shipments. Our quality protocols are designed to support cGMP and ISO standards for reliable and reproducible performance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥97.0%
Related Substances (HPLC)	Total impurities ≤3.0%
Single Unknown Impurity	≤1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.