Description

Methyl 2-Amino-6-(Trifluoromethyl)Nicotinate is a high-value, multi-functional heterocyclic building block. This compound is critical for the synthesis of complex molecules, particularly in the pharmaceutical and agrochemical sectors, due to its unique trifluoromethyl-substituted pyridine core. It is primarily sought after by research institutions and industrial manufacturers for developing novel active ingredients. The product is supplied to meet the stringent purity and consistency requirements of advanced chemical synthesis.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), especially in kinase inhibitor and antiviral drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Material Science Research: Serves as a precursor for functionalized ligands and organic electronic materials due to its electron-deficient aromatic system.
• Chemical Biology: Employed as a building block for synthesizing molecular probes and labeled compounds for biochemical studies.
• Custom Synthesis & Contract Manufacturing: A vital starting material for fine chemical companies offering bespoke synthesis services to the life sciences industry.

Basic Information

Product Name	Methyl 2-Amino-6-(Trifluoromethyl)Nicotinate
CAS No.	1034131-63-9
Molecular Formula	C8H7F3N2O2
Molecular Weight	220.15 g/mol
Synonyms	2-Amino-6-(trifluoromethyl)nicotinic acid methyl ester; Methyl 2-amino-6-(trifluoromethyl)pyridine-3-carboxylate; 3-Pyridinecarboxylic acid, 2-amino-6-(trifluoromethyl)-, methyl ester; 6-(Trifluoromethyl)-2-aminonicotinic acid methyl ester; 2-Amino-6-trifluoromethylnicotinic acid methyl ester
EINECS	Contact for details

Quality Control

Every batch of Methyl 2-Amino-6-(Trifluoromethyl)Nicotinate is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high-purity standards required for research and commercial synthesis. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profiles as determined by HPLC, NMR, and other relevant analytical techniques.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which may affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.