Description

5-Ethynylpyridine-2-Methanol is a versatile pyridine derivative featuring both an ethynyl and a hydroxymethyl functional group, making it a valuable bifunctional building block in advanced organic synthesis. Its molecular architecture is critical for constructing complex heterocyclic frameworks and functionalized ligands. This compound is primarily sought after by researchers and process chemists in the pharmaceutical, agrochemical, and material science industries for developing active ingredients and novel polymers.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Ligand Synthesis: Used to create sophisticated chelating ligands for catalysis and metal-organic frameworks (MOFs).
• Agrochemical Research: Employed in the development of new herbicides and pesticides with specific modes of action.
• Material Science: Acts as a monomer or cross-linking agent for producing specialty polymers with tailored electronic or mechanical properties.
• Chemical Biology: Utilized in click chemistry applications and as a probe for bioconjugation due to its alkyne functionality.
• Academic & R&D: A fundamental reagent for methodological studies in organic chemistry and heterocycle construction.

Basic Information

Product Name	5-Ethynylpyridine-2-Methanol
CAS No.	1033705-77-9
Molecular Formula	C8H7NO
Molecular Weight	133.15 g/mol
Synonyms	2-(Hydroxymethyl)-5-ethynylpyridine; 5-Ethynyl-2-pyridinemethanol; (5-Ethynyl-2-pyridinyl)methanol; 5-Ethynyl-2-(hydroxymethyl)pyridine; 2-Pyridinemethanol, 5-ethynyl-; 5-Ethynylpyridin-2-ylmethanol
EINECS	Contact for details

Quality Control

Our 5-Ethynylpyridine-2-Methanol is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with customer specifications and industry standards for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound may be hygroscopic; keep the container tightly sealed under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.