Description

3-Chloro-5-(trifluoromethyl)-2-pyridinecarbohydrazide is a high-purity, multi-functional heterocyclic building block of significant commercial interest. Its molecular structure, featuring both a reactive hydrazide group and halogenated pyridine core, makes it a versatile intermediate for synthesizing complex molecules. This compound is primarily utilized by pharmaceutical and agrochemical R&D teams engaged in the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting enzyme inhibitors and receptor modulators.
• Agrochemical Synthesis: Serves as a crucial precursor in the manufacture of advanced crop protection agents, including herbicides and insecticides, leveraging the bioactivity of the pyridine and trifluoromethyl motifs.
• Chemical Research & Development: Used as a specialized building block in organic synthesis for constructing complex heterocyclic compounds and functional materials.
• Ligand and Catalyst Preparation: The hydrazide functionality allows for its use in the preparation of chelating ligands and organocatalysts for various chemical transformations.

Basic Information

Product Name	3-Chloro-5-(trifluoromethyl)-2-pyridinecarbohydrazide
CAS No.	1033463-30-7
Molecular Formula	C7H5ClF3N3O
Molecular Weight	239.58 g/mol
Synonyms	3-Chloro-5-(trifluoromethyl)picolinohydrazide; 2-Pyridinecarbohydrazide, 3-chloro-5-(trifluoromethyl)-; 3-Chloro-5-trifluoromethylpyridine-2-carbohydrazide; 3-Chloro-5-(trifluoromethyl)-2-pyridinecarboxylic acid hydrazide; 3-Chloro-5-(trifluoromethyl)picolinic acid hydrazide; 1033463-30-7; 3-Chloro-5-(trifluoromethyl)pyridine-2-carbohydrazide
EINECS	Contact for details

Quality Control

Our 3-Chloro-5-(trifluoromethyl)-2-pyridinecarbohydrazide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee compliance with your research and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.