Description

Methyl 6-[4-(Trifluoromethyl)Piperidino]Nicotinate CAS NO 1033463-23-8 is a high-value, functionalized nicotinate derivative featuring a trifluoromethyl-substituted piperidine moiety. This compound is a critical pharmaceutical intermediate and research chemical prized for its unique structural properties that influence the pharmacokinetics and binding affinity of target molecules. It is primarily sought by pharmaceutical R&D teams and fine chemical manufacturers engaged in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas like oncology and central nervous system (CNS) disorders.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially kinase inhibitors and receptor modulators.
• Agrochemical Research: Used in the development of advanced pesticides and herbicides, leveraging the trifluoromethyl group for enhanced bioactivity and stability.
• Material Science: Serves as a precursor for specialty chemicals and functional materials, including liquid crystals and organic semiconductors.
• Academic & Contract Research: Employed in medicinal chemistry programs for structure-activity relationship (SAR) studies and library synthesis.
• Chemical Biology: Utilized as a probe or labeling agent in biochemical assays and diagnostic research.

Basic Information

Product Name	Methyl 6-[4-(Trifluoromethyl)Piperidino]Nicotinate
CAS No.	1033463-23-8
Molecular Formula	C13H15F3N2O2
Molecular Weight	288.27 g/mol
Synonyms	Methyl 6-(4-(trifluoromethyl)piperidin-1-yl)nicotinate; 6-(4-(Trifluoromethyl)-1-piperidinyl)-3-pyridinecarboxylic acid methyl ester; 3-Pyridinecarboxylic acid, 6-[4-(trifluoromethyl)-1-piperidinyl]-, methyl ester; Methyl 6-(4-(trifluoromethyl)piperidino)nicotinate; 1033463-23-8
EINECS	Contact for details

Quality Control

Our production of Methyl 6-[4-(Trifluoromethyl)Piperidino]Nicotinate adheres to stringent quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support cGMP standards for advanced applications and ensure compliance with relevant global regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.