Description

5-Chloro-1-(2-Chloro-6-Fluorobenzyl)-6-Oxo-1,6-Dihydro-3-Pyridinecarbaldehyde is a high-purity, advanced pharmaceutical intermediate characterized by its unique halogenated pyridinecarbaldehyde structure. This compound matters as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), enabling the development of targeted therapies. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in medicinal chemistry, particularly for projects involving kinase inhibitors and other small-molecule drug candidates.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of complex drug molecules, especially kinase inhibitors.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new therapeutic agents.
• Active Pharmaceutical Ingredient (API) Development: Serves as a core scaffold for constructing final API molecules in pre-clinical and clinical development stages.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.
• Chemical Reference Standard: Utilized as an analytical standard for quality control and method validation in API production.

Basic Information

Product Name	5-Chloro-1-(2-Chloro-6-Fluorobenzyl)-6-Oxo-1,6-Dihydro-3-Pyridinecarbaldehyde
CAS No.	1033463-20-5
Molecular Formula	C13H8Cl2FNO2
Molecular Weight	316.11 g/mol
Synonyms	5-Chloro-1-[(2-chloro-6-fluorophenyl)methyl]-6-oxo-1,6-dihydropyridine-3-carbaldehyde; 3-Pyridinecarbaldehyde, 5-chloro-1-[(2-chloro-6-fluorophenyl)methyl]-1,6-dihydro-6-oxo-; 1033463-20-5; 5-Chloro-1-(2-chloro-6-fluorobenzyl)-6-oxo-1,6-dihydro-3-pyridinecarboxaldehyde; 1-(2-Chloro-6-fluorobenzyl)-5-chloro-6-oxo-1,6-dihydro-3-pyridinecarbaldehyde
EINECS	Contact for details

Quality Control

Our 5-Chloro-1-(2-Chloro-6-Fluorobenzyl)-6-Oxo-1,6-Dihydro-3-Pyridinecarbaldehyde is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is easily oxidized and should be stored under an inert atmosphere such as nitrogen or argon for long-term stability. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.