Description

7-Amino-8-Bromo-2-Methylimidazo[1,2-A]Pyridine is a high-purity, advanced pharmaceutical intermediate characterized by its unique fused heterocyclic structure. This compound matters for its critical role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex molecular architectures. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of new drug candidates, especially within medicinal chemistry and process R&D.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the multi-step synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used as a scaffold or building block for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• API Development: Integral to the process development and scale-up of new Active Pharmaceutical Ingredients (APIs) requiring the imidazopyridine core.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and target validation.
• Contract Research & Manufacturing (CRAM): Supplied to CDMOs and CROs for custom synthesis projects and pilot-scale production.
• Academic Research: Utilized in university and institutional labs for fundamental research in heterocyclic chemistry and synthetic methodology.

Basic Information

Product Name	7-Amino-8-Bromo-2-Methylimidazo[1,2-A]Pyridine
CAS No.	1033434-88-6
Molecular Formula	C8H8BrN3
Molecular Weight	226.07 g/mol
Synonyms	8-Bromo-7-amino-2-methylimidazo[1,2-a]pyridine; 2-Methyl-7-amino-8-bromoimidazo[1,2-a]pyridine; 7-Amino-8-bromo-2-methyl-imidazo[1,2-a]pyridine; Imidazo[1,2-a]pyridine, 7-amino-8-bromo-2-methyl-; 1033434-88-6; AI3-52075; ZINC000103259757; SCHEMBL2180625
EINECS	Contact for details

Quality Control

Our 7-Amino-8-Bromo-2-Methylimidazo[1,2-A]Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for pharmaceutical R&D and scale-up. Certificates of Analysis (COA) with detailed batch-specific results are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Recommended long-term storage at 2-8°C for optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.