Description

2,5-Dibromopyridin-4-Ol is a high-purity brominated pyridine derivative, a crucial halogenated heterocyclic building block in advanced organic synthesis. Its value lies in its dual bromine substituents, which provide distinct, reactive sites for selective cross-coupling reactions and further functionalization. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, serving as a key intermediate in the development of active ingredients and complex molecular scaffolds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the pyridine core contributes to biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis for fine chemical production.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport layers or light-emitting components.
• Cross-Coupling Reactions: The bromine atoms are excellent handles for Suzuki, Stille, and Buchwald-Hartwig amination reactions to construct complex biaryl and heteroaryl systems.
• Chemical Biology Probes: Utilized to create tagged molecules or inhibitors for studying enzyme function and biological pathways.

Basic Information

Product Name	2,5-Dibromopyridin-4-Ol
CAS No.	1033203-55-2
Molecular Formula	C5H3Br2NO
Molecular Weight	252.89 g/mol
Synonyms	4-Hydroxy-2,5-dibromopyridine; 2,5-Dibromo-4-hydroxypyridine; 2,5-Dibromopyridin-4-ol; 4-Pyridinol, 2,5-dibromo-; 2,5-Dibromo-4-pyridinol
EINECS	Contact for details

Quality Control

Our 2,5-Dibromopyridin-4-Ol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat and incompatible materials. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.