Description

2,5-Dibromo-4-Chloropyridine is a halogenated pyridine derivative serving as a versatile and critical building block in advanced organic synthesis. Its value lies in its ability to undergo selective cross-coupling reactions, enabling the construction of complex molecular architectures. This intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries developing active ingredients and functional compounds.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and antiviral drug discovery programs.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the halogenated pyridine core provides bioactivity.
• Material Science Precursor: Serves as a monomer or functionalization agent in the synthesis of organic electronic materials, ligands for catalysts, and liquid crystals.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and Negishi couplings due to the differential reactivity of the bromine and chlorine substituents.
• Chemical Research & Development: A valuable tool for medicinal and process chemists in structure-activity relationship (SAR) studies and route scouting.
• Ligand Synthesis: Used to prepare polydentate nitrogen-based ligands for coordination chemistry and catalysis.

Basic Information

Product Name	2,5-Dibromo-4-Chloropyridine
CAS No.	1033203-47-2
Molecular Formula	C5H2Br2ClN
Molecular Weight	271.34 g/mol
Synonyms	4-Chloro-2,5-dibromopyridine; 2,5-Dibromo-4-chloropyridine; 4-Chloro-2,5-dibromopyridine; Pyridine, 2,5-dibromo-4-chloro-; 2,5-Dibromo-4-chloro-pyridine
EINECS	Contact for details

Quality Control

Our 2,5-Dibromo-4-Chloropyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.