Description

4-Chloro-5-Methylpyridin-2-Amine is a high-purity, functionalized pyridine derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where its specific substitution pattern enables precise molecular design. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to create novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A versatile synthon for the synthesis of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active compound research.
• Agrochemical Synthesis: Used as a precursor in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic core for bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport layers or molecular components for OLEDs.
• Custom Synthesis and Contract Manufacturing: A fundamental building block for custom chemical synthesis services catering to R&D and pilot-scale production.
• Academic and Industrial R&D: Used in exploratory chemistry for constructing complex heterocyclic libraries for high-throughput screening.

Basic Information

Product Name	4-Chloro-5-Methylpyridin-2-Amine
CAS No.	1033203-31-4
Molecular Formula	C6H7ClN2
Molecular Weight	142.59 g/mol
Synonyms	2-Amino-4-chloro-5-methylpyridine; 4-Chloro-5-methyl-2-pyridinamine; 5-Methyl-4-chloropyridin-2-amine; 4-Chloro-5-methyl-2-aminopyridine; 2-Pyridinamine, 4-chloro-5-methyl-; 4-Chloro-5-methylpyridin-2-ylamine; 4-Chloro-5-methyl-2-pyridineamine
EINECS	Contact for details

Quality Control

Our 4-Chloro-5-Methylpyridin-2-Amine is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, ensuring full traceability and compliance with your internal quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.