Description

2-(4-Methoxybenzyloxy)-5-(Trifluoromethyl)Pyridine is a high-purity, advanced pharmaceutical intermediate characterized by its distinct pyridine core functionalized with methoxybenzyloxy and trifluoromethyl groups. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of novel active pharmaceutical ingredients (APIs) targeting a range of therapeutic areas. It is primarily sought after by R&D laboratories and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, especially those requiring the bioisosteric and metabolic stability properties imparted by the trifluoromethyl group.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the pyridine moiety is a common structural feature.
• Ligand Synthesis: Serves as a precursor for creating specialized ligands in catalysis and material science applications.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and target engagement.
• Organic Electronic Materials: Potential starting material for the development of organic semiconductors and functional materials due to its aromatic system.

Basic Information

Product Name	2-(4-Methoxybenzyloxy)-5-(Trifluoromethyl)Pyridine
CAS No.	1033202-62-8
Molecular Formula	C14H12F3NO2
Molecular Weight	283.25 g/mol
Synonyms	5-(Trifluoromethyl)-2-[(4-methoxyphenyl)methoxy]pyridine; 2-[(4-Methoxybenzyl)oxy]-5-(trifluoromethyl)pyridine; 2-(4-Methoxybenzyloxy)-5-trifluoromethylpyridine; 4-Methoxybenzyl 5-(trifluoromethyl)pyridin-2-yl ether; 1033202-62-8
EINECS	Contact for details

Quality Control

Every batch of 2-(4-Methoxybenzyloxy)-5-(Trifluoromethyl)Pyridine is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency meet the exacting standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. For long-term storage, consider inert atmosphere conditions to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.