Description

4-Bromo-1-Methyl-1H-Pyrazolo[3,4-C]Pyridine is a high-value brominated heterocyclic building block essential for modern pharmaceutical and agrochemical research. This compound serves as a critical synthetic intermediate, enabling the construction of complex molecular architectures through versatile cross-coupling and functionalization reactions. It is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical industry for the discovery and synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of kinase inhibitors, anticancer agents, and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with novel modes of action.
• Material Science: Serves as a precursor for organic electronic materials, such as ligands for OLEDs and other functional polymers.
• Chemical Biology: Employed in the design and synthesis of molecular probes and tool compounds for target validation and mechanistic studies.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Stille, and Buchwald-Hartwig amination reactions.
• Library Synthesis: A versatile scaffold for generating diverse compound libraries in high-throughput screening campaigns.

Basic Information

Product Name	4-Bromo-1-Methyl-1H-Pyrazolo[3,4-C]Pyridine
CAS No.	1032943-41-1
Molecular Formula	C8H6BrN3
Molecular Weight	224.06 g/mol
Synonyms	1-Methyl-4-bromo-1H-pyrazolo[3,4-c]pyridine; 4-Bromo-1-methylpyrazolo[3,4-c]pyridine; 1H-Pyrazolo[3,4-c]pyridine, 4-bromo-1-methyl-; 4-Bromo-1-methyl-1H-pyrazolo[3,4-c]pyridine; 1032943-41-1; 4-Br-1-Me-Pyrazolo[3,4-c]pyridine
EINECS	Contact for details

Quality Control

Our 4-Bromo-1-Methyl-1H-Pyrazolo[3,4-C]Pyridine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We support development and commercial projects with material that meets the stringent standards required for pharmaceutical R&D.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.