Description

1H-Pyrrolo[2,3-B]Pyridine-5-Carboxaldehyde, 4-Chloro-1-(Phenylsulfonyl)- is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. Its unique molecular scaffold, featuring a pyrrolopyridine core with chloro and phenylsulfonyl substituents, makes it a critical intermediate for constructing complex pharmacophores. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the discovery and development of new active ingredients. Its precise structure enables targeted modifications, accelerating the creation of novel compounds with potential therapeutic or pesticidal activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors, anticancer agents, and other small-molecule drug candidates targeting various disease pathways.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for bioactivity.
• Material Science: Serves as a building block for creating specialized organic electronic materials, ligands for catalysis, and advanced polymers.
• Chemical Biology & Proteomics: Employed in the design of molecular probes, tags, and linkers for studying biological systems and protein functions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and fine chemical manufacturers for use in client-specific, multi-step synthetic routes.
• Academic & Institutional Research: Utilized in university and government laboratories for fundamental studies in synthetic methodology and heterocyclic chemistry.

Basic Information

Product Name	1H-Pyrrolo[2,3-B]Pyridine-5-Carboxaldehyde, 4-Chloro-1-(Phenylsulfonyl)-
CAS No.	1032815-07-8
Molecular Formula	C14H9ClN2O3S
Molecular Weight	320.75 g/mol
Synonyms	4-Chloro-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine-5-carbaldehyde; 4-Chloro-1-tosyl-1H-pyrrolo[2,3-b]pyridine-5-carboxaldehyde; 4-Chloro-1-(benzenesulfonyl)-1H-pyrrolo[2,3-b]pyridine-5-carboxaldehyde; 1H-Pyrrolo[2,3-b]pyridine-5-carboxaldehyde, 4-chloro-1-(phenylsulfonyl)-; 1032815-07-8; 4-Chloro-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine-5-carboxaldehyde; 4-Chloro-1-tosylated pyrrolo[2,3-b]pyridine-5-carbaldehyde
EINECS	Contact for details

Quality Control

Every batch of 1H-Pyrrolo[2,3-B]Pyridine-5-Carboxaldehyde, 4-Chloro-1-(Phenylsulfonyl)- is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the identity, purity, and consistency required for sensitive research and scale-up processes. A detailed Certificate of Analysis (COA) is supplied with each shipment, typically including results from HPLC, NMR, and mass spectrometry. Our quality commitment supports compliance with cGMP and ISO standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or when opening the container to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.