Description

tert-Butyl 5-Bromopyridin-2-Yl(Ethyl)Carbamate is a high-value, protected intermediate crucial for modern synthetic chemistry. This compound is specifically designed to facilitate the controlled introduction of functionalized pyridine moieties into complex molecular architectures. It is primarily utilized by pharmaceutical and agrochemical R&D teams, as well as by fine chemical manufacturers, for the synthesis of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides that require a functionalized bromopyridine core.
• Ligand Synthesis: Serves as a precursor for creating sophisticated ligands used in catalysis and material science.
• Chemical Biology Probes: Employed in the construction of molecular probes for studying biological pathways and target engagement.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille) to form biaryl structures.
• Custom Synthesis: Provides a versatile starting point for contract research and manufacturing organizations (CROs/CMOs) to produce bespoke compounds for clients.

Basic Information

Product Name	tert-Butyl 5-Bromopyridin-2-Yl(Ethyl)Carbamate
CAS No.	1032758-85-2
Molecular Formula	C12H17BrN2O2
Molecular Weight	301.18 g/mol
Synonyms	5-Bromo-N-ethyl-N-(pyridin-2-yl)carbamic acid tert-butyl ester; tert-Butyl N-ethyl-N-(5-bromopyridin-2-yl)carbamate; 2-[(tert-Butoxycarbonyl)(ethyl)amino]-5-bromopyridine; Carbamic acid, N-(5-bromo-2-pyridinyl)-N-ethyl-, 1,1-dimethylethyl ester; N-Ethyl-N-(5-bromo-2-pyridinyl)carbamic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Every batch of tert-Butyl 5-Bromopyridin-2-Yl(Ethyl)Carbamate is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency suitable for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.