Description

4-Bromo-2-(Bromomethyl)Pyridine is a versatile and highly functionalized pyridine derivative, serving as a critical bifunctional building block in advanced organic synthesis. Its dual reactive sites—a bromine atom on the pyridine ring and a bromomethyl group—enable precise molecular construction, making it indispensable for creating complex heterocyclic architectures. This compound is primarily sought after by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Building block for creating novel herbicides, fungicides, and insecticides with enhanced efficacy.
• Ligand and Catalyst Development: Used to construct sophisticated pyridine-based ligands for transition metal catalysis and coordination chemistry.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of organic electronic materials and metal-organic frameworks (MOFs).
• Cross-Coupling Reactions: Essential substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl systems.
• Nucleophilic Substitution: The bromomethyl group is highly reactive towards various nucleophiles, facilitating the introduction of diverse functional groups.

Basic Information

Product Name	4-Bromo-2-(Bromomethyl)Pyridine
CAS No.	1032650-53-5
Molecular Formula	C6H5Br2N
Molecular Weight	250.92 g/mol
Synonyms	2-(Bromomethyl)-4-bromopyridine; 4-Bromo-2-bromomethylpyridine; Pyridine, 4-bromo-2-(bromomethyl)-; 4-Bromo-2-(bromomethyl)pyridine; 2,4-Dibromomethylpyridine (incorrect but common alias); 4-Bromo-2-pyridinemethanol, bromo derivative
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-(Bromomethyl)Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment ensures the material meets the stringent requirements for research and process development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.