Description

4-(3-Nitro-Phenyl)-3-Oxo-Butyric Acid Methyl Ester is a high-purity, versatile organic intermediate characterized by its nitro-phenyl and β-keto ester functional groups. This compound is a critical building block in advanced organic synthesis, enabling the construction of complex molecular architectures for pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and agrochemical industries for the synthesis of active pharmaceutical ingredients (APIs) and novel bioactive compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex heterocyclic compounds and potential drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging its nitro-aromatic moiety.
• Organic Synthesis Building Block: Serves as a versatile substrate for Michael additions, cyclocondensation reactions, and other transformations to create libraries of compounds for screening.
• Material Science Research: Employed in the development of organic semiconductors, dyes, and photoactive materials due to its conjugated electron-withdrawing groups.
• Academic & Industrial R&D: Essential for methodological studies in synthetic organic chemistry and for scaling up novel synthetic routes.

Basic Information

Product Name	4-(3-Nitro-Phenyl)-3-Oxo-Butyric Acid Methyl Ester
CAS No.	1032507-14-4
Molecular Formula	C11H11NO5
Molecular Weight	237.21 g/mol
Synonyms	Methyl 4-(3-Nitrophenyl)-3-oxobutanoate; 3-Oxo-4-(3-nitrophenyl)butyric Acid Methyl Ester; Methyl 3-Oxo-4-(m-nitrophenyl)butyrate; 4-(m-Nitrophenyl)-3-oxobutyric Acid Methyl Ester; β-Keto Ester Derivative; 3-Nitrophenyl Acetoacetate Methyl Ester; Butyric acid, 3-oxo-4-(3-nitrophenyl)-, methyl ester
EINECS	Contact for details

Quality Control

Our production of 4-(3-Nitro-Phenyl)-3-Oxo-Butyric Acid Methyl Ester adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our quality system is designed to meet the rigorous standards required for pharmaceutical and advanced chemical research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is moisture-sensitive; ensure the container is kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.