Description

4-Amino-2-Chloronicotinaldehyde 2,2,2-Trifluoroacetate is a high-purity, advanced pharmaceutical intermediate and versatile building block in organic synthesis. This compound is critical for research and development in medicinal chemistry, particularly for constructing complex nitrogen-containing heterocycles. It is primarily sought after by pharmaceutical companies, agrochemical R&D labs, and fine chemical manufacturers for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, especially kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with novel modes of action.
• Chemical Synthesis: Serves as a versatile precursor for the preparation of complex pyridine and nicotinaldehyde derivatives.
• Material Science: Potential monomer or precursor for functional polymers and advanced organic materials.
• Academic & Contract Research: Essential reagent for methodological studies and library synthesis in academic and CRO (Contract Research Organization) settings.

Basic Information

Item	Detail
Product Name	4-Amino-2-Chloronicotinaldehyde 2,2,2-Trifluoroacetate
CAS No.	1032350-07-4
Molecular Formula	C8H5ClF3N2O3
Molecular Weight	269.58 g/mol
Synonyms	4-Amino-2-chloropyridine-5-carboxaldehyde 2,2,2-trifluoroacetate; 2-Chloro-4-aminonicotinaldehyde trifluoroacetate; 5-Formyl-2-chloro-4-aminopyridine trifluoroacetate; 4-Amino-2-chloro-5-pyridinecarboxaldehyde TFA salt; 2-Chloro-4-amino-5-pyridinecarbaldehyde 2,2,2-trifluoroacetic acid salt
EINECS	Contact for details

Quality Control

Our 4-Amino-2-Chloronicotinaldehyde 2,2,2-Trifluoroacetate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting cGMP (current Good Manufacturing Practice) compliance for use in regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if possible to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.