Description

tert-Butyl 1-(4-(3-Hydroxy-9-Phenyl-[1,2,4]Triazolo[3,4-F][1,6]Naphthyridin-8-Yl)Phenyl)Cyclobutylcarbamate is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound is critical for research and development in medicinal chemistry, offering a sophisticated building block for novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers focused on oncology and targeted drug discovery.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of novel small-molecule drug candidates, particularly in oncology research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes to develop new therapeutic entities.
• API Synthesis: Serves as a crucial building block in the multi-step synthesis of complex Active Pharmaceutical Ingredients (APIs).
• Biochemical Research: Employed in the study of enzyme inhibition and receptor binding assays for target validation.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production of clinical trial materials.
• Academic Research: Utilized in university and institutional labs for cutting-edge research in heterocyclic and naphthyridine chemistry.

Basic Information

Product Name	tert-Butyl 1-(4-(3-Hydroxy-9-Phenyl-[1,2,4]Triazolo[3,4-F][1,6]Naphthyridin-8-Yl)Phenyl)Cyclobutylcarbamate
CAS No.	1032350-03-0
Molecular Formula	C30H27N5O3
Molecular Weight	505.57 g/mol
Synonyms	1,6-Naphthyridine-8-carboxamide, N-[1-[[4-(3-hydroxy-9-phenyl[1,2,4]triazolo[3,4-f][1,6]naphthyridin-8-yl)phenyl]cyclobutyl]carbamic acid 1,1-dimethylethyl ester; tert-Butyl [1-[4-(3-hydroxy-9-phenyl-[1,2,4]triazolo[3,4-f][1,6]naphthyridin-8-yl)phenyl]cyclobutyl]carbamate; BOC-protected naphthyridine-triazole intermediate; 1032350-03-0
EINECS	Contact for details

Quality Control

Our tert-Butyl 1-(4-(3-Hydroxy-9-Phenyl-[1,2,4]Triazolo[3,4-F][1,6]Naphthyridin-8-Yl)Phenyl)Cyclobutylcarbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client requirements for research or cGMP applications.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. The compound is light-sensitive and should be handled under inert atmosphere when appropriate for prolonged stability.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.