Description

1-Methyl-1-(6-Trifluoromethyl-Pyridin-3-Yl)-Ethylamine Hydrochloride is a high-purity, advanced pharmaceutical intermediate characterized by its pyridine-based structure with a trifluoromethyl substituent. This compound is critical for research and development in medicinal chemistry, offering a versatile building block for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new therapeutic agents, particularly in areas requiring fluorinated compounds for enhanced metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders, inflammation, and infectious diseases.
• Agrochemical Research: Used in the development of new generation pesticides and herbicides, where the trifluoromethylpyridine moiety can contribute to improved efficacy and environmental profile.
• Medicinal Chemistry R&D: A valuable scaffold for structure-activity relationship (SAR) studies and lead optimization programs in both academic and industrial settings.
• Fluorinated Compound Synthesis: Acts as a precursor for introducing the trifluoromethylpyridine group into more complex molecules, leveraging fluorine's unique properties.
• Ligand and Catalyst Development: Potential use in creating specialized ligands for catalysis or in material science applications.

Basic Information

Product Name	1-Methyl-1-(6-Trifluoromethyl-Pyridin-3-Yl)-Ethylamine Hydrochloride
CAS No.	1031721-46-6
Molecular Formula	C9H12ClF3N2
Molecular Weight	240.65 g/mol
Synonyms	1-(6-(Trifluoromethyl)pyridin-3-yl)-N-methylethan-1-amine hydrochloride; α-Methyl-6-(trifluoromethyl)-3-pyridineethanamine hydrochloride; 1-Methyl-1-[6-(trifluoromethyl)-3-pyridinyl]ethylamine hydrochloride; 1-(6-Trifluoromethyl-pyridin-3-yl)-ethyl-methyl-amine hydrochloride; N-Methyl-1-[6-(trifluoromethyl)pyridin-3-yl]ethan-1-amine hydrochloride
EINECS	Contact for details

Quality Control

Our 1-Methyl-1-(6-Trifluoromethyl-Pyridin-3-Yl)-Ethylamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, which includes data from HPLC, NMR, and mass spectrometry. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.